​BIBIRINE, or Bebeerine, C₁₉H₂₁NO₃, an alkaloid obtained from the bark and fruit of the greenheart (q.v.) tree, Nectandra rodiaei, called bibiru or sipiri in Guiana, where the tree grows. The substance was discovered about the year 1835 by Hugh Rodie, a surgeon in Demerara, who used it as a febrifuge in substitution for quinine.