​OWEGO, a village and the county-seat of Tioga county. New York, U.S.A., on the Owego Creek and on the N. side of the Susquehanna river, 21 m. W. of Binghamton. Pop. (1910, U.S. census) 4633. It is served by the Erie, the Lehigh Valley and the Delaware, Lackawanna & Western railways; a branch of the last connects with Ithaca, N.Y. Owego occupies the site of an Indian (probably Tuscarora) village named “Ah-wa-ga,” which was destroyed by General James Clinton in 1779. The name, of which “Owego” is a corruption, is said to mean “where the valley widens.” A white settlement and trading post were set up here in 1785, and the village of Owego was incorporated in 1827.