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|-style="text-align:center;" |colspan=2|Table of Diagnostic Points in Quinine and Malarial Amblyopia (see p. 75) |-style="text-align:center;font-variant:small-caps;border-top:1px solid black;border-bottom:1px solid black;" |Quinine Amblyopia ||style="border-left:1px solid black;"|Malarial Amblyopia |- |History.—Quinine taken in large doses, not less than 30 grains. ||style="border-left:1px solid black;"|History.—Quinine may have been taken, but not necessarily in large doses. |- |Onset.—Sudden, accompanied by deafness; both eyes are affected. ||style="border-left:1px solid black;"|Onset.—Not usually sudden, but it may be so if hæmorrhage has occurred in the macular region. There is no deafness, and both eyes are not necessarily affected. |- |Pupils.—Widely dilated, and whilst loss of vision continues they do not react to light. ||style="border-left:1px solid black;"|Pupils.—React to light. |- |Vision.—Completely lost for a time. ||style="border-left:1px solid black;"|Vision.—Never completely lost. |- |Ophthalmoscopic appearances.—A white haze over fundus; cherry-red spot at macula; optic disc pale; retinal vessels markedly constricted. ||style="border-left:1px solid black;"|Ophthalmoscopic appearances.—There is optic neuritis; optic disc is of characteristic greyish-red colour; retinal hæmorrhages, and sometimes vitreous opacities. |- |Termination.—Usually some permanent defect in the field of vision or in colour vision. Central vision recovers first; optic disc is unusually white, and retinal vessels small. ||style="border-left:1px solid black;"|Termination.—Some cases recover completely; in others greater or less permanent defect of vision remains. |-style="vertical-align:text-top;" |Treatment.—Stop quinine. Amyl nitrite has been recommended to induce dilatation of retinal vessels. ||style="border-left:1px solid black;"|Treatment.—Give quinine. |}