Giant solitary trichoepithelioma

Giant solitary trichoepithelioma is a cutaneous condition characterized by a skin lesion that may be up to several centimetres in diameter.[1]: 672 

Giant solitary trichoepithelioma
SpecialtyDermatology, oncology Edit this on Wikidata

Signs and symptoms

Giant solitary trichoepithelioma primarily affects the perianal and groin region.[2] They typically measure a few centimeters in diameter and rarely reach 2 to 3 cm.[3]

Diagnosis

Giant solitary trichoepithelioma is distinguished histologically by a dermal or subcutaneous tumor made up of basophilic cells grouped in solid, adenoid, or lace-like clusters. The cells have a sparse cytoplasm and a darkly pigmented nucleus, and the tumor islands exhibit the typical peripheral cell palisading. Papillary bodies and trichilemmal keratinization in horn cysts are indicative of a solid diagnosis, however they are not always present. Failures to develop papillary mesenchyme are represented by papillary bodies.[4]

Treatment

The preferred course of treatment is either radiosurgical ablation or surgical excision, with or without a flap.[4]

See also

References
  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. Teli, Bhavuray; Thrishuli, P. B.; Santhosh, R.; Amar, D. N.; Rajpurohit, Shravan (2015). "Giant solitary trichoepithelioma". South Asian Journal of Cancer. 04 (01). Georg Thieme Verlag KG: 041–044. doi:10.4103/2278-330x.149951. ISSN 2278-330X. PMC 4382785.
  3. Genc, Selahattin; Sirin Ugur, Seher; Arslan, Ilker Burak; Demir, Ahmet; Tuhanioglu, Birgul; Kuskonmaz, Ibrahim; Eruyar, Tugrul; Selcuk, Adin (2012). "A Giant Solitary Trichoepithelioma Originating from the Auricle". Dermatologic Surgery. 38 (9): 1527–1528. doi:10.1111/j.1524-4725.2012.02483.x. ISSN 1076-0512.
  4. Swaroop, MukundaRanga; Sathyanarayana, BelagolaDassegowda; Chaurasia, PriyankaKumari; Devaraj, Yogesh; Dukkipati, Monica; Sajid, Aneesa (2017). "Giant solitary trichoepithelioma over the nose". Indian Journal of Dermatopathology and Diagnostic Dermatology. 4 (1): 17. doi:10.4103/ijdpdd.ijdpdd_65_16. ISSN 2349-6029.

Further reading
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