If you think about it, we ourselves are only information. So if we could find a reliable way of reading all this information stored within us, especially the information that makes up our brains, we could upload it.
I mean, theoretically speaking, we can upload this information in a computer (a computer designed for this purpose), and live forever. We just need to figure out how to make this computer learn more things like we do ourselves to increase our information.
One other thing would be, "Can we simulate creativity?"