A number of complications come from 2x gravity.
First any fall would be considerably more deadly. My (at the time) 60-year-old mother broke her wrist fairly badly by simply falling down in a Home Depot parking lot. She has no medical conditions that impair the strength of her bones; that's just life. 2x the gravity would likely increase this threat. I assume some sort of soft exoskeleton would be normal for day-to-day, and a more robust hard suit when anything physical was involved.
Simply standing up and walking would be challenging, if not impossible. A 200 pound athletic man would suddenly be lugging around 400 pounds, and would not be able to run (likely at all) or even travel very far distances. For this reason the exoskeleton likely needs to be upgraded with robotics to take pressure off the muscles.
Blood pressure is also an issue. To quote a source:
Under normal conditions, your body must maintain 22 millimeters of
mercury blood pressure to get blood from your heart to your brain.
Each additional +Gz (blood flows from the head to the feet) that a
person experiences multiplies that requirement: The body has to muster
double that at 2g, triple that at 3g, and so on until they hit around
4 or 5 G's, at which point most folks will pass out due to oxygen
starvation because all the blood stays in their feet.
This condition is known as G-LOC (G-induced loss of consciousness).
Fighter pilots, with the aid of flight suits packed with air bladders
that force blood out of the lower extremities as well as specialized
breathing and tension techniques, can be trained to withstand up to 9
+Gz.
So the exoskeleton also should provide external pressure like a flight suit to allow blood pressure to be maintained.
Further still the increase in atmospheric pressure (from the increase in gravity) would make it harder to breathe in and out, while simultaneously forcing extra gasses in your bloodstream including oxygen and less-than-ideal other gasses included. We could negate both of these issues by suiting entirely up with oxygen tanks and a sealed mask, or we'll have to accept the drudgery of simply breathing and carefully terraform the atmosphere to an ideal composition.
Likely buildings will be built around asinine safety with railing common, stairs rare, and most floors designed to provide traction.
Transportation costs will be significantly more, and flight will be expensive enough that most long-range transportation will depend on railcars designed to avoid frictional costs.
Chairs will likely be reclined to be more comfortable, since the human body is designed to handle Earth's gravity, not sitting up in 2x, and even with the exosuits it will likely still be more comfortable to simply not avoid fighting gravity as much as possible.
The people will likely be unusually muscular even in ways that you normally would not expect (for example, muscle builders don't exercise blinking, but in this world every blink rips down muscles considerably more and the body will respond to try to build them back up stronger).
Toys will likely be far less physical-activity focused with again a concern for safety.
Cooking will be changed since the boiling point of water will be considerably higher, and any chemical reaction to add air to food (such as yeast causing bread to rise) will fantastically fail, most likely, producing dense food.
Most plants from Earth simply won't survive; as plants depend on osmosis to draw water up, they depend on osmosis being stronger than the force of Earth's gravity. In a 2x gravity world this likely will no longer be the case. Thus if this new world doesn't come with plants, the colonists will likely have to depend on plantstuff for food to be shipped to them from off world.
Credit to @DaaaahWoosh for some of the ideas.