What would be the best way to permanently increase a human's speed, strength, stamina, and durability? I'm looking to create a world in which the majority of humans realize how weak and feeble their bodies actually are and they have found a way to change this. However, I need help on the actual "way". I'm not scientific at all but I don't want to be cliche by giving them a serum or a pill. I was looking for something that would require surgery. The use of some sort of technology would be ideal but it is not absolutely necessary.
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11I think you are wrong in stating humans are feeble and lacking stamina. Humans developed a really high endurance, making them able to hunt in the savana by chasing the pray until its exaustion. There is almost no animal capable of competing with a human on the 40+ km range. – L.Dutch Apr 10 '17 at 05:39
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18Have you considered workout? ;-) – Burki Apr 10 '17 at 06:44
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8To add to L.Dutch. Few species requires as little sleep as us too. Most predators like cats sleep for long period. Our closest competators in endurance are horses and wolves. Which just happen to be two of our top domesticated species. – Mormacil Apr 10 '17 at 09:11
8 Answers
At least for stamina, you could read up about "the man who can run forever": Dean Karnazes (https://www.theguardian.com/lifeandstyle/the-running-blog/2013/aug/30/dean-karnazes-man-run-forever).
Karnazes' ability to run for inhuman distances seems par for the course with other endurance athletes, but what sets him apart is that he honestly does not show signs of muscle fatigue AT ALL. The article explains it all, but if you want a quick summary, here it is:
Basically, your muscles send out fatigue signals when lactic acid builds up from anaerobic exertion - this is when you begin to feel tired. For Karnazes, his body clears lactic acid so efficiently that his muscles never send such signals, and thus he never feels tired. As such, he can basically keep up a decent running pace for as long as he can stay awake.
How does this relate to your question? Imagine that you were able to create some nanobot with the ability to metabolize lactic acid. Inject this nanobot into your subject, and voila! He now has superhuman stamina.

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3I feel like even if the Muscles were no longer sending the fatigue signal, you could still do serious damage to them if you did not let them rest. Sure, you could simply stop someone feeling pain, but then they won't know when something goes wrong. If the person can't feel when their muscles are getting tired, then they wont be able to tell when they need to stop and rest. – SGR Apr 10 '17 at 10:36
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6@SGR We are not talking about blocking pain signals, the issue is is that under intense exercise anaerobic respiration causes lactic acid to build up in your muscles, When this amount of lactic acid hits a specific level the muscles trigger impulses to your brain that your brain interprets as "my muscles are over-exerted and need to rest to give the lactic acid time to clear", which is what makes you feel fatigued and wanting to stop. If you clear the lactic acid as quick as it is produced, the muscles will never fatigue. – James T Apr 10 '17 at 12:31
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1@JamesTrotter You wouldn't personally feel fatigue, but I assume your muscles would still be damaged if you went past their "limit". – SGR Apr 10 '17 at 13:01
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4@SGR what "limit"? What biological process would damage muscles from over-use in the absence of the root cause of muscle fatigue? – Apr 10 '17 at 14:48
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3@SGR If (as in this answer) nanobots simply took over lactic acid clearing duties, then the result would eliminate fatigue and leave pain reception. If one were actually damaging muscle tissue from over-exertion the subject would still feel pain. – rwfeather Apr 10 '17 at 15:33
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1@Snowman - So you think the body is just randomly outputting the lactic acid for the thrill of it all? The body tends to do things for a reason. It is a reasonable assumption that the body is creating the lactic acid to prevent the person from "over-exerting" the muscles. :rweather If damaging muscle tissue from over-exertion caused pain on its own then I doubt the body would have evolved to having the need for creating the lactic acid. Whether any of that is true or not, I have no idea but they seem like a reasonable assumptions. However, the OP's answer is great as it is supported by science – Dunk Apr 10 '17 at 16:15
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1@Dunk I think you misunderstand what causes the lactic acid. It isn't produced as a signal, it is produced as a waste product when a muscle does work. The buildup of lactic acid is what causes muscle fatigue, it isn't the signal of muscle fatigue. If you can clear the lactic acid quickly enough, your muscles won't become fatigued at all – Kevin Apr 10 '17 at 16:21
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3@Dunk no, the body is not creating lactic acid for the "thrill." Nor is it a reasonable assumption that lactic acid is simply there to prevent over-exertion. Lactic acid is a waste product from the chemical processes that power muscle (sugar -> energy + waste). Blood can only cart it away so fast. The answer suggests using nanobots to cart lactic acid away faster, so it does not build up and cause fatigue. – Apr 10 '17 at 16:29
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@Snowman - Your last comment which includes the reason why would have been far superior to your previous comment which basically said something akin to "that's stupid". We can disagree on "reasonable assumption", but I still think it was a reasonable assumption. I was just trying to stand up for SGR because I thought he made a very good point. – Dunk Apr 10 '17 at 16:54
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@SGR: thanks for the comment, which made me realise my answer could be more explicit. As mentioned, lactic acid is the root cause of muscle fatigue AND damage, so removing it solves the problem you speak of: i.e. no signals of fatigue are received because no damage is incurred. Of course, mechanical damage such as tears still can happen - this solution does not cover that possibility. – Xenocacia Apr 11 '17 at 01:13
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So — you are saying that Karnazes uses nanobots to help clear away lactic acid? Is he the Million–Dollar Man? – can-ned_food Apr 21 '17 at 21:54
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@can-ned_food: no, I am saying that Karnazes has the natural ability to clear away lactic acid (no one is 100% sure why, best guess is genetic pre-disposition), but a future with sufficiently sophisticated nanobots could artificially imbue anyone with that same ability. – Xenocacia Apr 22 '17 at 04:38
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I'm another that feels the muscles will find another limit. @Snowman - to your question, muscles may still be damaged by wear and friction, the little muscle tears with over-exertion that signal more muscle is needed. Or starvation, since lactic acid needs to be cleared away, so the blood not removing it fast enough may also not supply the muscles' other needs fast enough. Also, fewer breaks probably means overheating more. Removing the lactic acid via nanobots should give a fair boost, since fatigue hits first... but other damage is less easy. – Megha May 30 '17 at 07:35
The thing to remember is that every attribute comes with a cost. Cheetahs are fast — but they have almost no fat reserves, and not much of anything else. Race horses have been bred to be really fast — but are always on the edge of breaking legs by overdoing what they do best. For humans — muscles consume a significant amount of our food resources, even at rest. That's why they atrophy very quickly if not used. Our big brains are supposed to be useful (they've allowed us to conquer the whole planet) but use about a third of the calories we consume. Plus, too strong, you could break bones or dislocate joints.
There's a very good short story by Larry Niven called "Brenda". It discusses the problems with breeding super warriors — double gene for night vision causes daytime blindness, doubled gene for blood clot (stop wounds bleeding) leads to blood clots and stroked by age 40 or 50. And so on.
The fastest are rarely the strongest; pick one or the other (look at the Olympics). Plus, human scale is designed for the size we are. Bigger, taller, or carrying a bigger load means thicker bones meaning slower running. Unless you're looking for some magical formula where the muscles operate say, 20% more efficiently.
The same one that works now, exercise and training. If you want to make your new human more fit, just make them enjoy exercise more than normal humans. Minimal changes to the human, just a few changes to the initial wiring of the brain, and it can be spread organically(breeding) or artificially (genetic manipulation). If going to gym was as pleasurable as going to the strip joint, bar, or dunkin donuts you would have a stronger, faster and more fit populace.

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“If going to gym was as pleasurable as going to the strip joint, bar, or dunkin donuts […]” Oh, wow. What a scenario that conjures. – can-ned_food Apr 21 '17 at 21:57
I imagine that you could use implanted stem cells to increase muscle mass, as these cells will usually change into whatever kind of tissue surrounds them. This solution would improve speed and strength.
By combining stem cells with genetic modification you could theoretically create entirely new organs to implant in a human. This isn't even too far fetched based on modern science. The genome editing molecule known as CRISPR-Cas9 is relatively new, but allows scientists to splice DNA from different organisms together with much more specificity than was ever previously possible. With this technology you could give people bird hearts and lungs (which are much more efficient than mammals') or something even more amazing.
If you want more inspiration, I recommend looking through this link detailing the process to create a Space Marine in the Warhammer 40,000 Universe.
They have extra hearts and lungs for added stamina, and they take dietary supplements which add different minerals to their bones for more durability.

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2+1 for more efficient parts from other animals. Lots of our organs can't improve further because the have hit a local maximum. But evolution has already produced more efficient versions in other species. – user31389 Apr 10 '17 at 13:15
Get Rid of Chemical Energy
Muscles are simply polymers. An electrical signal tells them to wind themselves up (contract) or unwind (relax). They're not very good ones either, but they've got an amazing amount of control, ultimately using a chemical as an energy source ATP -> ADP, and generating a waste product (lactic acid) for this energy conversion. Overall it's messy and irreversible, which causes the non-linear strength, speed, and stamina problems. The reaction rates simply can't happen fast enough for all three to be increased simultaneously.
Using Electrical Energy
By converting to Electroactive Polymers, a type of artificial muscle, the waste product is simply the drop in voltage. Stamina is unlimited - so long as you have an electric source, you're muscles keep working. Does your laptop complain "it's tired"? No! It complains it's battery is out. So long as you have futuristic energy storage, this isn't going to be a problem.
To add strength, increase the voltage. To add speed, increase the current. If you have limited energy storage, increasing one of these will necessitate decreasing another. But with unlimited energy, then all three could be enhanced well beyond human limits.
Cyborgs then, requires technology and surgery.
Your weak arm muscles? replaced with basically a nanoweave of hydralics
Bones? Bah we use titanium
They can be powered both by electricity/converting fat/stealing energy from the digestive tract.
Another route would be to simply have worked out a more efficient cell structure/ biological processes, a more efficient way of binding oxygen could improve the supply of oxygen to the cells etc. There are many inefficiencies in the human body that could be improved upon.

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You could make them really big, like giants, and hope that it would scale these stats up - they'd be faster because their legs would be longer, more durable because things wouldn't hurt them as much because "oh it's just a little scratch", and they probably wouldn't need as much stamina - but they'd need to eat a lot more to sustain their huge size.

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2The problem with making creatures larger is that you quickly run into what is known as the square-cube law: for example, strength grows by square, but mass grows by cube, so effective strength is down. Compare Can you simply scale up animals? which discusses this at some length. – user Apr 10 '17 at 09:58
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@MichaelKjörling true, they would still be stronger than other things around them which would be fine for fighting, but that would be a huge problem for scaling up other things that don't involve fighting. I suppose this idea depends on where OP is going with this. – Styxal Apr 10 '17 at 10:09
A very permanent way would be altering the human genetic code. Not only would this alteration enhance the human you first use it on, the change is going to remain evident throughout the rest of their descendants as well. We already use genetic therapy on foodstuffs to increase their quantity and quality.
Genetic therapy already exists for humans and involves inserting genes to fix problems instead of drugs or surgery. For some genetic conditions this is the only course of action that will succeed. In the case of humans you would find desirable traits and locate the code that works with these traits. For example, once all code related to metabolism is understood, you could change the genetic code to ensure a person gets the most out of every meal they have with little waste.
The most realistic method would be to simply remove any and all defects that will possibly transfer via genetics or bloodline. History of heart disease? Wiped out. Genetic disposition for astigmatism? Wiped out. You'll be able to undo or prevent an assortment of problems from ever occurring.
This does open up the potential to have an ugly backlash though, an unforeseen issue that might arise with the tampering could be difficult to fix, and it's not something that will just go away either.
A better way to look at it would be the ability to have the maximum human potential. You'll still have to act on it. The greatest genetic sequence in the world won't make a musclebound monster of a man if you never exercise or pick up weights.
(I've never given an answer before so sorry if this does something wrong)

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(Oops, hitting enter causes it to post). I'm unsure how much detail to provide. Genetic therapy already exists for humans and involves inserting genes to fix problems instead of drugs or surgery. For some genetic conditions this is the only course of action that will succeed. In the case of humans you would find desirable traits and locate the code that works with these traits. For example, once all code related to metabolism is understood, you could change the genetic code to ensure a person gets the most out of every meal they have with little waste. – Friendlysociopath Apr 10 '17 at 14:00
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What would be changed with genetic modification? Chimerical swapping of limbs and organs? Changing hormone proportions? Et c. Otherwise a decent enough answer, i.m.o., but with one caveat: I, too, prefer to answer a question on so far as is necessary to help a diligent worldbuilder over some hurdle; however, this question was tagged science-based, and so probably means that the asker needs assistance explaining some of the technologies required. – can-ned_food Apr 21 '17 at 21:50
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P.s. a comment asking “can you elaborate” shouldn't be answered with a comment unless to ask in something in return; your comment should be edited–in to the answer. :-) – can-ned_food Apr 21 '17 at 21:50
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